I don't think there would be so many other options left other than Toronto, which I think is being made too.
Are you serious Umberto?
CYYC (Calgary AB) Very large airport. Second parallel runway to be finished next year. Whole new section of terminal. Whole airport area/size is equivalant to that of CYVR.
CYEG (Edmonton AB), CYWG (Winnipeg MB) Not massive but not tiny either. Much much larger than either Lihue - Hilo or Kona or Kahului, and you did those airports and they sold well.
Since CYVR is on the west coast, there are hundreds of flights to points within Canada. The problem is they are all east and the nearest airport to date is CYUL (Montreal). I did this flight last week. Air time was 5 hours 8 minutes. Not the type of flight I want to make on a weekly basis on the simulator. CYYC/CYEG are just over 1 hour flight time with many daily flights. Flights from either CYVR or CYUL to CYWG take about 3 hours, not short but not overly long either.
Of course I also do flights south to KLAS, KSFO, and KLAX but flights to major hubs in Canada suck using default scenery. Even Orbx does very little to enhance CYYC or CYEG. Perhaps airports such as CYWG and places like CYQR (Regina SK) could be sold in packs, much like the Hawaiian airports were. Other than CYYC, these other airports are smaller but they are certainly busy on a daily and nightly basis and get arriving and departing flights from many U.S. and International carriers. All these airports see see a large variety of aircraft including all the heavies. Just as CYUL sold well, so too I believe would these other airports as they are comparable in size. Just my thoughts...
Cheers,
Thad