If the MSFS 2020 stops at the "loading fase", the answer is the file "190_E658703.dll" of the nvidia app after the new 572.42 driver release.
This file is located at "C:\ProgramData\NVIDIA\NGX\" folder. Renaming or deleting it fix the issue for me. (But be careful, dont know what this files really do, rename them is better)
The strange thing is that in windows event viewer, the file that shows as crash is the "Couatl64_MSFS.exe" one. Dont know why. That´s because i went here to see if people were getting this issue too.
Source:
https://www.reddit.com/r/MicrosoftFlightSim/comments/1idhxks/msfs_2020_ctd_during_loading_event_viewer_says/EDIT: Doing a "Clean Nvidia Driver" reinstall corrected the issue for me too (No need to delete/rename anything)
