You are showing an error code that is related to GSX, but in your screenshot there's another error that doesn't have anything to do with GSX, it's the usual VRAM exhaustion error, which is completely unrelated to GSX and it's known to affect P3D V5 in DX12 when your settings are too high and you finished your VRAM. P3D4 would just slow down, but P3D V5 will crash if you are out of VRAM, we can only hope this will improve with future updates.
DGXI errors are graphic errors but, in P3D V5 of our software module, there's no DirectX code anywhere, for the precise reason users won't assume GSX crashed their sim, because of DirectX, so you can be sure the error in the screenshot is not caused by GSX, but it's possible GSX can be affected by it, maybe because the sim stopped talking with GSX in the meantime because of its error.