When you are editing a door using the 3D editor, pressing Y to exit the 3D and going back to the dialog, will have all the modications saved automatically, that's why the "Apply" is greyed, it's as if it was just Applied ( by exiting the editor ) so, you can be sure the changed you made in the 3D editor HAS been saved.
Instead, when editing something in the numeric dialog, the Apply button will become active and waiting to be pressed to save the changes.