Does anyone have a suggestions as to what would cause this and a suggestion to fix it?
The error is displayed because the audio driver reported your audio device had a problem when calling OpenAL, which is the standard audio library we use for sound in GSX.
This might be a problem of the drivers supporting OpenAL, but also a temporary problem, possibly because the headset was turned off or in stand-by when GSX started. Headsets can be tricky, I just bought a new one yesterday, because it randomly disappeared from Skype...
Other than being sure the headset is fully working *before* you start the sim, there's not much you can do.
It should also be possible to just "Restart Couatl" when trying, without restarting the whole sim.