We never, ever, had a similar report before in several years that GSX uses Python 2.7. You are the 2nd ever reporting it, and the only other report was a few days ago. However, we distributed that library ( Python27.dll ) since many years, and nothing has changed in the latest updates.
Do you have another FSX application that also use Python, which has installed an incompatible version ? What addons you installed recently ?
I've noticed that Aerosoft Alta X configurator program comes with that .DLL, but I don't have any errors, and it shouldn't affect GSX, since it's installed in its own folder, unless you keep the program open while FSX starts.