I am having this same issue as well. But I did manage to see a pop up window that referenced an issue with FSUIPC. I just recently updated that program on my machine a couple of days back to the latest version available. I am not saying that is the issue, just offering as a possible clue as to a conflict between the two programs.
I also had an older version of SODE installed which the setup program said it would try to remove before installing a newer version.
I will try to prevent loading FSUIPC upon FSX start via the XML file or something similar and see if that corrects the issue.
I do not use any anti virus software and run the setup exe with the Run As Admin option.
Mark